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Mind-body disorder theory

Psychotherapy based treatments

One of the first references to the concept of an "irritable bowel" appeared in the Rocky Mountain Medical Journal in 1950.[30] The term was used to categorize patients who developed symptoms of diarrhea, abdominal pain, constipation, but where no well-recognized infective cause could be found.

Early theories suggested that the Irritable Bowel was caused by a psychosomatic, or mental disorder. One paper from the 1980s investigated "learned illness behavior" in patients with IBS and peptic ulcers.[31] Another study suggested that both IBS and stomach ulcer patients would benefit from 15 months of psychotherapy.[32] Later, it would be found that most stomach ulcers were caused by a bacterial infection with Helicobacter pylori.[33]

Additional publications suggesting the role of brain-gut "axis" appeared in the 1990s, such as a study entitled Brain-gut response to stress and cholinergic stimulation in IBS published in the Journal of Clinical Gastroenterology in 1993.[34] A 1997 study published in Gut magazine suggested that IBS was associated with a "derailing of the brain-gut axis."[35]

 
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